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pentobarbital will lessen the extent or impact of abemaciclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration of abemaciclib with sturdy CYP3A4 inducers lowers plasma focus of abemaciclib and its metabolites.In a long time past, barbiturates have been a common Portion of basic anesthe